Author

C. J. Bustamante

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 4 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:long-read sequencing· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

B. Onoa· 2 shared J. Kim· 2 shared J. P. Castillo· 2 shared R. P. Sosa· 2 shared A. B. Tong· 1 shared A. Cassago· 1 shared A. Chen· 1 shared A. F. Florez-Ariza· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersBiophysics

B. Onoa

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Nanopore molecular trajectories of a eukaryotic reverse transcriptase reveal a long-range RNA structure sensing mechanism

A. Shaw, J. M. Craig, H. Amiri, J. Kim, H. E. Upton, S. C. Pimentel, J. R. Huang, S. Marqusee, J. H. Gundlach, K. Collins, C. J. Bustamante

The paper uses nanopore sequencing to study the single-nucleotide kinetics of a reverse transcriptase, revealing its ability to sense and destabilize RNA structures during cDNA synthesis.

bioRxiv · Apr 5, 2023 · PreprintBiophysics

Actin-driven protrusions generate rapid long-range membrane tension propagation in cells

H. De Belly, S. Yan, H. Borja da Rocha, S. Ichbiah, J. P. Town, H. Turlier, C. J. Bustamante, O. D. Weiner

The paper uses optogenetics and optical tweezers to show that actin-driven protrusions enable rapid, long-range membrane tension propagation, contrasting with localized force application.

bioRxiv · Sep 7, 2022 · PreprintCell Biology

Assignment of structural transitions during mechanical unwrapping of nucleosomes and their disassembly products

C. D. Diaz-Celis, C. Canari-Chumpitaz, R. P. Sosa, J. P. Castillo, M. Zhang, E. Cheng, A. Chen, M. Vien, J. Kim, B. Onoa, C. J. Bustamante

This study uses optical tweezers and FRET to identify DNA segments unwrapped during nucleosome mechanical transitions, revealing distinct low- and high-force unwrapping processes.

bioRxiv · Apr 13, 2022Biophysics

Friction-driven membrane scission by the human ESCRT-III proteins CHMP1B and IST1

A. K. Cada, M. Remec Pavlin, J. P. Castillo, A. B. Tong, K. P. Larsen, X. Ren, A. L. Yokom, F.-C. Tsai, J. Shiah, P. Bassereau, C. J. Bustamante, J. H. Hurley

This study shows that CHMP1B and IST1 can sever membranes through a friction-driven mechanism, requiring constriction and extensional force, but not VPS4 or spastin.

bioRxiv · Feb 3, 2022 · PreprintBiophysics

Interactions of Upstream and Downstream Promoter Regions with RNA Polymerase are Energetically Coupled and a Target of Regulation in Transcription Initiation

R. P. Sosa, A. F. Florez-Ariza, C. Diaz Celis, B. Onoa, A. Cassago, P. S. L. de Oliveira, R. V. Portugal, D. G. Guerra, C. J. Bustamante

bioRxiv · May 13, 2020 · PreprintBiophysics