Author

C. Cayron

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Pathology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Approach:biophysical modeling· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

B. Thibault· 3 shared J. Guillermet-Guibert· 3 shared N. Therville· 3 shared A. Carrier· 2 shared A. V. Villard· 2 shared C. Basset· 2 shared C. Cintas· 2 shared F. Pont· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

B. Thibault

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Meat enriched-diet and inflammation promote PI3Kα-dependent pancreatic cell plasticity that limit tissue regeneration.

C. Cayron, D. Bozoglou, A. V. Villard, G. Reyes-Castellanos, N. Therville, R. Baer, S. Arcucci, N. Naud, M. Tosolini, F. Pont, D. Ferreira Da Mota, F. Gueraud, C. Basset, A. Carrier, F. Pierre, , J. Guillermet-Guibert

This study shows that meat-enriched diets and inflammation promote pancreatic cell plasticity via PI3Kα, which limits tissue regeneration and increases cancer risk.

bioRxiv · Aug 22, 2023 · PreprintPathology

Phosphoproteomics identifies PI3K inhibitor-selective adaptive responses in pancreatic cancer cell therapy and resistance

C. Cintas, T. Douche, Z. Dantes, E. Mouton-Barbosa, M.-P. Bousquet, C. Cayron, N. Therville, F. Pont, F. Ramos-Delgado, C. Guyon, B. Garmy-Susini, P. Cappello, O. Burlet-Schiltz, E. Hirsch, A. Gomez-Brouchet, , J. Guillermet-Guibert

This study identifies adaptive phosphoprotein responses to isoform-selective PI3K inhibitors in pancreatic cancer, showing that combination therapy can overcome resistance.

bioRxiv · Oct 8, 2020Cancer Biology

Pancreatic Cancer Intrinsic PI3Kα Activity accelerates Metastasis and rewires Macrophage Component

B. Thibault, F. Ramos-Delgado, E. Pons-Tostivint, N. Therville, C. Cintas, S. Arcucci, S. Cassant-Sourdy, G. Reyes-Castellanos, M. Tosolini, A. V. Villard, C. Cayron, R. Baer, J. Bertrand-Michel, D. Payen, H. Yan, , J. Guillermet-Guibert

This paper identifies PI3K pathway activation as a driver of metastatic progression in pancreatic cancer and shows that targeting PI3K can delay macro-metastatic evolution.

bioRxiv · Sep 23, 2020Cancer Biology