Author

M.-P. Bousquet

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:proteomics· 4 Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:protein folding & dynamics· 2 Approach:biophysical modeling· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

O. Burlet-Schiltz· 3 shared D. Zivkovic· 2 shared J. Marcoux· 2 shared T. Menneteau· 2 shared A. Gomez-Brouchet· 1 shared A. I. Lamond· 1 shared A. Sanchez Dafun· 1 shared A. Schahl· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersCancer Biology

O. Burlet-Schiltz

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Cancer BiologyMolecular Cancer TherapeuticsPeer-reviewedDec 3, 2021

Phosphoproteomics identifies PI3K inhibitor-selective adaptive responses in pancreatic cancer cell therapy and resistance

C. Cintas, T. Douche, Z. Dantes…·J. Guillermet-Guibert

This study identifies adaptive phosphoprotein responses to isoform-selective PI3K inhibitors in pancreatic cancer, showing that combination therapy can overcome resistance.

DOI 10.1158/1535-7163.mct-20-0981

humanproteomics

𝕏 PostBluesky

BiochemistrybioRxivJun 18, 2021

Proteasome complexes experience profound structural and functional rearrangements throughout mammalian spermatogenesis

D. Zivkovic, A. Sanchez Dafun, T. Menneteau…·M.-P. Bousquet

This study maps proteasome composition and interactomes during spermatogenesis, revealing structural and functional changes in the spermatoproteasome (s20S) and its role in germ cell differentiation.

DOI 10.1073/pnas.2116826119

mouseproteomics

𝕏 PostBluesky

BiophysicsbioRxivMay 5, 2020

Conformational maps of human 20S proteasomes reveal PA28- and immuno-dependant inter-ring crosstalks

J. Lesne, M. Locard-Paulet, J. Parra…·J. Marcoux

The paper uses HDX-MS to show conformational differences between human 20S proteasomes and their PA28 activators, revealing allosteric changes upon binding.

DOI 10.1038/s41467-020-19934-z

humanproteomics

𝕏 PostBluesky

Cell BiologybioRxivMar 27, 2018

PIP30/FAM192A is a novel regulator of the nuclear proteasome activator PA28gamma

B. Jonik-Nowak, T. Menneteau, D. Fesquet…·O. Coux

This paper identifies PIP30/FAM192A as a novel cofactor of PA28gamma, showing it binds to PA28gamma and modulates its interactions with the 20S proteasome and coilin.

DOI 10.1073/pnas.1722299115

humanproteomics

𝕏 PostBluesky