ImmunologyACS Chemical BiologyPeer-reviewed
Carbohydrate sulfation as a mechanism for fine-tuning Siglec ligands
J. Jung, J. R. Enterina, D. T. Bui…·M. S. Macauley
This study shows that specific sulfate modifications on Siglec ligands, mediated by CHSTs, can enhance or reduce Siglec binding, with implications for cancer immune evasion.
DOI 10.1021/acschembio.1c00501