Increasing phagocytosis of microglia through targeting CD33 with liposomes displaying glycan ligands
A. Bhattacherjee, G. Daskhan, A. Bains, A. E. S. Watson, G. Eskandari-Sedighi, C. D. St. Laurent, A. Voronova, M. S. Macauley
This study shows that CD33L liposomes enhance microglia phagocytosis by multivalently engaging CD33, with effects dependent on CD33's glycan-binding and signaling properties.
bioRxiv · May 8, 2021Immunology