FAM13A regulates KLRG1 expression and interferon gamma production of natural killer cells
N. Zeng, M. Theresine, C. Capelle, N. Patil, C. Masquelier, C. Davril, A. Baron, D. Coowar, X. Dervillez, A. Poli, C. Leonard, R. Balling, M. Ollert, J. Zimmer, F. Q. Hefeng
This study shows that FAM13A depletion increases KLRG1 and reduces IFN-gamma production in NK cells, leading to increased lung metastases in a mouse model.
bioRxiv · Aug 26, 2020 · PreprintImmunology