Author

X. Dervillez

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1

Frequent Co-Authors

J. Zimmer· 3 shared B. Brandus· 2 shared C. Seguin-Devaux· 2 shared G. Iserentant· 2 shared A. Baron· 1 shared A. Poli· 1 shared C. Capelle· 1 shared C. Davril· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersImmunology

J. Zimmer

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Complement-Activating Multimeric Immunotherapeutic Complexes for HER2-breast cancer immunotherapy

C. Seguin-Devaux, B. Brandus, J.-M. Plesseria, G. Iserentant, J.-Y. Servais, G. Kanli, I. Behrmann, J. Zimmer, J. H. COHEN, X. Dervillez

This study develops and tests CoMiX immunotherapeutics that activate complement to kill HER2-positive breast cancer cells, showing significant tumor growth inhibition in xenograft models.

bioRxiv · Feb 2, 2024 · PreprintImmunology

Natural Killer activating Multimeric Immunotherapeutic compleXes (NaMiX) induce cytotoxic activity and killing of HIV-1 infected cells

R. Schober, B. Brandus, T. Laeremans, G. Iserentant, G. Dessilly, J. Zimmer, M. Moutschen, J. L. Aerts, X. Dervillez, C. Seguin-Devaux

This study develops NaMiX, multimeric immunotherapeutics targeting NK cell checkpoints, which enhance NK cell cytotoxicity against HIV-1 infected cells and reduce viral DNA in mice.

bioRxiv · Nov 11, 2022 · PreprintImmunology

FAM13A regulates KLRG1 expression and interferon gamma production of natural killer cells

N. Zeng, M. Theresine, C. Capelle, N. Patil, C. Masquelier, C. Davril, A. Baron, D. Coowar, X. Dervillez, A. Poli, C. Leonard, R. Balling, M. Ollert, J. Zimmer, F. Q. Hefeng

This study shows that FAM13A depletion increases KLRG1 and reduces IFN-gamma production in NK cells, leading to increased lung metastases in a mouse model.

bioRxiv · Aug 26, 2020 · PreprintImmunology