Author

F. Q. Hefeng

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Assay:flow cytometry· 1

Frequent Co-Authors

M. Ollert· 4 shared R. Balling· 3 shared A. Baron· 2 shared C. Capelle· 2 shared C. Leonard· 2 shared D. Coowar· 2 shared N. Zeng· 2 shared S. Cire· 2 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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4 shared papersImmunology

M. Ollert

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4 papers

Recent·Most cited

Altered infective competence of the human gut microbiome in COVID-19

L. de Nies, V. Galata, C. Martin-Gallausiaux, M. Despotovic, S. B. Busi, C. J. Snoeck, L. Delacour, D. P. Budagavi, C. C. Laczny, J. Habier, P.-C. Lupu, R. Halder, J. V. Fritz, T. Marques, E. Sandt, , P. Wilmes

This study identifies increased virulence factors and antimicrobial resistance genes in the gut microbiome of COVID-19 patients, suggesting heightened infective competence.

bioRxiv · Oct 20, 2022 · PreprintMicrobiology

DJ-1 depletion slows down immunoaging in T-cell compartments

N. Zeng, C. Capelle, A. Baron, S. Cire, C. Leonard, D. Coowar, H. Koseki, A. M. Westendorf, J. Buer, D. Brenner, R. Krüger, R. Balling, M. Ollert, F. Q. Hefeng

This study shows that DJ-1 depletion delays immunoaging in T-cell compartments in both humans and mice by preserving non-senescent T cells and affecting hematopoietic and naive-CD8-intrinsic mechanisms.

bioRxiv · May 21, 2021Immunology

Standard PBMC cryopreservation selectively decreases detection of nine clinically-relevant T-cell markers

C. M. Capelle, S. Cire, W. Ammerlaan, M. Konstantinou, R. Balling, F. Betsou, A. Cosma, M. Ollert, F. Q. Hefeng

This study shows that standard PBMC cryopreservation reduces detection of nine T-cell markers but not others, highlighting potential issues in clinical trial interpretations.

bioRxiv · May 18, 2021Immunology

FAM13A regulates KLRG1 expression and interferon gamma production of natural killer cells

N. Zeng, M. Theresine, C. Capelle, N. Patil, C. Masquelier, C. Davril, A. Baron, D. Coowar, X. Dervillez, A. Poli, C. Leonard, R. Balling, M. Ollert, J. Zimmer, F. Q. Hefeng

This study shows that FAM13A depletion increases KLRG1 and reduces IFN-gamma production in NK cells, leading to increased lung metastases in a mouse model.

bioRxiv · Aug 26, 2020 · PreprintImmunology