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2 papers
Recent·Most cited
R. Lipsh-Sokolik, O. Khersonsky, S. P. Schroder, C. de Boer, S. Y. Hoch, G. J. Davies, H. S. Overkleeft, S. J. Fleishman
The paper introduces CADENZ, a machine-learning strategy for designing structurally diverse enzymes, achieving a tenfold improved hit rate and over 10,000 active enzymes.
bioRxiv · Sep 17, 2022Bioengineering
M. Mann, A. Mehta, C. de Boer, M. S. Kowalczyk, K. Lee, N. Rogel, A. R. Knecht, D. Farouq, A. Regev, D. Baltimore
The paper shows that aged hematopoietic stem cells exhibit a myeloid-biased transcriptional response to inflammation, which is linked to Klf5, Ikzf1, and Stat3.
bioRxiv · Nov 14, 2017Immunology