Single cell profiling of immature human postnatal thymocytes resolves the complexity of intra-thymic lineage differentiation and thymus seeding precursors.
M. Lavaert, K. L. Liang, N. Vandamme, J.-E. Park, J. Roels, M. S. Kowalczyk, B. Li, O. Ashenberg, M. Tabaka, D. Dionne, T. L. Tickle, M. Slyper, O. Rozenblatt-Rosen, B. Vandekerckhove, G. Leclercq, , T. Taghon
The paper uses single-cell RNA sequencing to analyze immature human thymocytes and identifies thymus seeding precursors and T-lineage developmental pathways.
bioRxiv · Apr 7, 2020 · PreprintImmunology