Author

C. Denkert

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:whole-genome sequencing· 1

Frequent Co-Authors

A. V. Lee· 2 shared P. C. Lucas· 2 shared S. Oesterreich· 2 shared A. Bahreini· 1 shared A. Machleidt· 1 shared B. H. Park· 1 shared B. Ignold-Heppner· 1 shared B. Troness· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersCancer Biology

A. V. Lee

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2 papers

Recent·Most cited

Hotspot ESR1 mutations are multimodal and contextual drivers of breast cancer metastasis

Z. Li, Y. Wu, M. E. Yates, N. Tasdemir, A. Bahreini, J. Chen, K. M. Levine, N. M. Priedigkeit, S. Ali, L. Buluwela, S. Arnesen, J. Gertz, J. K. Richer, B. Troness, D. El-Ashry, , S. Oesterreich

This study identifies ESR1 mutations as drivers of breast cancer metastasis by altering cell adhesion and migration through genomic and transcriptomic reprogramming.

bioRxiv · Feb 10, 2021 · PreprintCancer Biology

Acquired mutations and transcriptional remodeling in long-term estrogen-deprived locoregional breast cancer recurrences

N. Priedigkeit, K. Ding, W. Horne, J. K. Kolls, T. Du, P. C. Lucas, J.-U. Blohmer, C. Denkert, A. Machleidt, B. Ignold-Heppner, S. Oesterreich, A. V. Lee

This study analyzes acquired mutations and transcriptional changes in long-term estrogen-deprived breast cancer recurrences, identifying common genetic and expression alterations associated with endocrine resistance.

bioRxiv · Jun 8, 2020Cancer Biology