Synthetic mycolates derivatives as molecular tools to decipher protein mycoloylation, a unique post-translational modification in bacteria.
E. Lesur, Y. Zhang, N. Dautin, C. Dietrich, I. Li de la Sierra-Gallay, L. Augusto, P. Rollando, N. Lazar, D. Urban, G. Doisneau, F. Constantinesco-Becker, H. Van Tilbeurgh, D. Guianvarc'h, Y. Bourdreux, N. Bayan
The paper identifies MytC as the mycoloyltransferase responsible for protein mycoloylation in Corynebacterium glutamicum and demonstrates its specificity for mycolate donors.
bioRxiv · Mar 28, 2024 · PreprintMicrobiology