Author

C. Fihn

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:bacteria (other)· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

E. E. Carlson· 2 shared A. Gilbertsen· 1 shared A. N. Murtha· 1 shared A. R. Villarreal· 1 shared D. Hung· 1 shared G. Vogt· 1 shared H. Lembke· 1 shared J. Gaulin· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersMicrobiology

E. E. Carlson

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Evaluation of Expanded 2-Aminobenzothiazole Library for Inhibition of Pseudomonas aeruginosa Virulence Phenotypes

C. Fihn, H. Lembke, J. Gaulin, P. Bouchard, A. R. Villarreal, M. R. Penningroth, K. Crone, G. Vogt, A. Gilbertsen, Y. Ayotte, L. CouthinodeOliveira, M. Serrano-Wu, N. Drouin, D. Hung, R. C. Hunter, E. E. Carlson

The paper evaluates a library of 2-aminobenzothiazole compounds targeting the CA domain of histidine kinases, finding they reduce virulence in Pseudomonas aeruginosa.

bioRxiv · May 2, 2023 · PreprintMicrobiology

High-level carbapenem tolerance requires antibiotic-induced outer membrane modifications.

A. N. Murtha, M. I. Kazi, R. D. Schargel, T. Cross, C. Fihn, E. E. Carlson, J. M. Boll, T. Dörr

This paper identifies PhoPQ-mediated LPS modifications as a mechanism for carbapenem tolerance in Enterobacterales, showing that antibiotic-induced outer membrane changes enhance survival.

bioRxiv · Sep 25, 2021Microbiology