The thiol methyltransferase activity of TMT1A (METTL7A) is conserved across species
J. M. Gonzalez Dalmasy, C. Fitzsimmons, W. J. E. Frye, A. J. Perciaccante, C. P. Jewell, L. M. Jenkins, P. J. Batista, R. W. Robey, M. M. Gottesman
This study shows that TMT1A's ability to methylate thiol-based HDAC inhibitors is conserved across species, suggesting its functional relevance in animal models.
bioRxiv · Nov 17, 2023Pharmacology & Toxicology