Author

C. G. Huber

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biochemistry· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:proteomics· 5 Approach:experimental assay· 4 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Organism:mouse· 2 Research Focus:cell-cell communication· 1 Approach:deep learning· 1

Frequent Co-Authors

J. Horejs-Hoeck· 3 shared C. Bloechl· 2 shared D. P. Elmer· 2 shared D. Strunk· 2 shared F. Aberger· 2 shared H.-H. Dang· 2 shared P. Winter· 2 shared R. Weiss· 2 shared

Activity by Year

2020-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersImmunology

J. Horejs-Hoeck

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

A functional corona around extracellular vesicles enhancesangiogenesis during skin regeneration and signals in immune cells

m. Wolf, R. Poupardin, E.-P. Patricia, C. Andre, C. Bloechl, A. Obermayer, G. G. Fausto, B. Vari, E. Eminger, H. M. Binder, A. M. Raninger, H. Sarah, G. Brachtl, A. Spittler, T. Heuser, , D. Strunk

This study shows that a functional protein corona on extracellular vesicles enhances angiogenesis and immune signaling, with corona removal inhibiting these effects.

bioRxiv · Sep 20, 2021 · PreprintCell Biology

The NLRP3/eIF2 axis drives cell cycle progression in acute myeloid leukemia

M. Luciano, C. Blöchl, J. Vetter, L. Urwanisch, T. Neuper, D. P. Elmer, R. Bauer, H.-H. Dang, H. Strandt, D. Neureiter, P. Krenn, S. Tesanovic, S. Rieser, O. Bergsleitner, L. Zell, , J. Horejs-Hoeck

This study shows that inhibiting the NLRP3 inflammasome reduces AML cell proliferation by promoting eIF2 phosphorylation and cell cycle arrest.

bioRxiv · Jun 25, 2021 · PreprintImmunology

Towards middle-up analysis of polyclonal antibodies: subclass-specific N-glycosylation profiling of murine immunoglobulin G (IgG) by means of HPLC-MS

C. Bloechl, C. Regl, C. G. Huber, P. Winter, R. Weiss, T. Wohlschlager

This paper develops a middle-up HPLC-MS workflow to profile subclass-specific N-glycosylation in murine polyclonal IgGs, revealing subclass and glycosylation shifts in immunized mice.

bioRxiv · Jul 16, 2020Biochemistry

Oncogenic GLI1 and STAT1/3 activation drives immunosuppressive tryptophan/kynurenine metabolism via synergistic induction of IDO1 in skin cancer cells

D. P. Elmer, V. Strobl, G. Stockmaier, H.-H. Dang, M. Wiederstein, D. Licha, A. Strobl, C. Sternberg, S. Tesanovic, S. Grund-Groeschke, W. Gruber, F. Wolff, R. Moriggl, A. Risch, R. Reischl, , F. Aberger

This study identifies IDO1-kynurenine pathway activation as a novel mechanism by which HH-IL6 and GLI-STAT signaling promote immunosuppression in skin cancer, suggesting combination therapy targeting these pathways.

bioRxiv · May 4, 2020 · PreprintCancer Biology

In silico design of Phl p 6 variants with altered folding stability significantly impacts antigen processing, immunogenicity and immune polarization

P. Winter, S. Stubenvoll, S. Scheiblhofer, I. A. Joubert, L. Strasser, C. Briganser, W. T. Soh, F. Hofer, A. S. Kamenik, V. Dietrich, S. Michelini, J. Laimer, P. Lackner, J. Horejs-Hoeck, M. Tollinger, , R. Weiss

bioRxiv · Feb 26, 2020Immunology