S. Scheiblhofer

Laser facilitated epicutaneous peptide immunization using dry patch technology

This study demonstrates that laser-assisted dry patch delivery of peptides with CpG-ODN1826 induces potent cytotoxic T cell responses in a mouse model.

Laser-facilitated epicutaneous immunization with SARS-CoV-2 spike protein induces ACE2 blocking antibodies in mice

In silico design of Phl p 6 variants with altered folding stability significantly impacts antigen processing, immunogenicity and immune polarization

Effect of structural stability on endolysosomal degradation and T-cell reactivity of major shrimp allergen tropomyosin

This study examines how structural stability of tropomyosins affects their endolysosomal degradation and T-cell reactivity across different invertebrate sources.

Laser-facilitated epicutaneous immunotherapy with hypoallergenic beta-glucan neoglycoconjugates suppresses lung inflammation and avoids local side effects in a mouse model of allergic asthma

This study shows that LamOVA, a hypoallergenic beta-glucan neoglycoconjugate, suppresses lung inflammation and reduces side effects in a mouse asthma model when delivered via laser-facilitated epicutaneous immunotherapy.

Mast cells and γδ T cells are largely dispensable for adaptive immune responses after laser-mediated epicutaneous immunization

This study shows that γδ T cells and mast cells are largely dispensable for adaptive immune responses after laser-mediated epicutaneous immunization, except for minor effects on IgG1 and effector T cells in mast cell-depleted mice.