Author

C. H. Choy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

R. J. Botelho· 2 shared C. Wallace· 1 shared E. Ospina-Escobar· 1 shared G. Lenk· 1 shared G. Saffi· 1 shared J. B. McPhee· 1 shared M. A. Gray· 1 shared N. Porco· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

R. J. Botelho

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2 papers

Recent·Most cited

Salmonella actively modulates TFEB in murine macrophages in a growth-phase and time-dependent manner

S. Inpanathan, E. Ospina-Escobar, V. C. Li, Z. Adamji, T. Lackraj, Y. H. Cho, N. Porco, C. H. Choy, J. B. McPhee, R. J. Botelho

This study shows Salmonella modulates TFEB in macrophages depending on its growth phase and infection time, with stationary-phase Salmonella delaying TFEB nuclear mobilization while late-log Salmonella allows TFEB activation.

Microbiology Spectrum · Jan 11, 2024Peer-reviewedCell Biology

Lysosome enlargement during inhibition of the lipid kinase PIKfyve proceeds through lysosome coalescence

C. H. Choy, G. Saffi, M. A. Gray, C. Wallace, R. M. Dayam, Z.-Y. A. Ou, G. Lenk, R. Puertollano, S. C. Watkins, R. J. Botelho

This study shows that PIKfyve inhibition causes lysosome coalescence, leading to fewer enlarged lysosomes, and that TFEB-mediated biosynthesis does not drive this swelling.

bioRxiv · Apr 5, 2018Cell Biology