Salmonella actively modulates TFEB in murine macrophages in a growth-phase and time-dependent manner
S. Inpanathan, E. Ospina-Escobar, V. C. Li, Z. Adamji, T. Lackraj, Y. H. Cho, N. Porco, C. H. Choy, J. B. McPhee, R. J. Botelho
This study shows Salmonella modulates TFEB in macrophages depending on its growth phase and infection time, with stationary-phase Salmonella delaying TFEB nuclear mobilization while late-log Salmonella allows TFEB activation.
bioRxiv · Dec 3, 2022Cell Biology