Author

C. H. Lee

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 5 Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 5 Organism:mouse· 5 Approach:experimental assay· 4 Assay:bulk RNA-seq· 2 Approach:deep learning· 2 Assay:imaging· 2 Assay:structural biology· 2 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

J. Zhang· 4 shared T. M. Arefin· 3 shared Z. Liang· 3 shared B. Tafech· 1 shared C. Moon· 1 shared C. Park· 1 shared D. H. Turnbull· 1 shared E. Cho· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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4 shared papersBioengineering

J. Zhang

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

APE1 associates with 60S ribosomes and tRNAs and regulates the expression of IGF2BP1

W. M. Li, B. Tafech, C. H. Lee

This study shows APE1 associates with 60S ribosomes and tRNAs in HepG2 cells and regulates IGF2BP1 translation, suggesting a tumor suppressor role in hepatocellular carcinoma.

bioRxiv · Dec 8, 2023 · PreprintBiochemistry

Multi-parametric MRI can detect enhanced myelination in the Gli1-/- mouse brain

C. H. Lee, M. Holloman, J. L. Salzer, J. Zhang

This study uses multi-parametric MRI to detect enhanced myelination in Gli1-/- mice, showing that combining T2, T1/T2, and radial diffusivity explains 80% of MBP variance in the corpus callosum.

bioRxiv · Nov 20, 2023 · PreprintBioengineering

Towards reliable reconstruction of the mouse brain thalamocortical connectivity using diffusion MRI

T. M. Arefin, C. H. Lee, Z. Liang, H. Rallapalli, Y. Z. Wadghiri, D. H. Turnbull, J. Zhang

This study optimizes dMRI tractography for reliable reconstruction of the mouse brain thalamocortical network by evaluating imaging and tractography parameters using an atlas and tracer data.

bioRxiv · Dec 28, 2022 · PreprintBioengineering

Peroxiredoxin 5 regulates osteogenic differentiation via interaction with hnRNPK during bone regeneration

E. Cho, X. Che, M. J. Ang, S. Cheon, J. Lee, K. Kim, C. H. Lee, S.-Y. Lee, H.-Y. Yang, C. Moon, C. Park, J.-Y. Choi, T.-H. Lee

This study identifies Prdx5's role in bone regeneration by regulating osteoblast differentiation through interaction with hnRNPK, impacting osteocalcin expression and osteoclast activity.

bioRxiv · Jun 9, 2022Cell Biology

Using Mesoscopic Tract-Tracing Data to Guide the Estimation of Fiber Orientation Distributions in the Mouse Brain from Diffusion MRI

Z. Liang, T. M. Arefin, C. H. Lee, J. Zhang

This study uses mesoscopic tract-tracing data to improve fiber orientation distribution estimation in mouse brains via deep learning, enhancing tractography specificity without sacrificing sensitivity.

bioRxiv · Jun 2, 2022Bioengineering

Oxo-M and 4-PPBP Delivery via Multi-Domain Peptide Hydrogel Toward Tendon Regeneration

G. Y. Park, S. Tarafder, S. L. Eyen, S. Park, R. Kim, Z. Siddiqui, V. Kumar, C. H. Lee

This study develops a multi-domain peptide hydrogel for controlled delivery of Oxo-M and 4-PPBP to enhance tendon regeneration in vivo.

bioRxiv · Aug 25, 2021Bioengineering

Virtual Mouse Brain Histology from Multi-contrast MRI via Deep Learning

Z. Liang, C. H. Lee, T. M. Arefin, Z. Dong, P. Walczak, S.-H. Shi, F. Knoll, Y. Ge, L. Ying, J. Zhang

This paper uses deep learning to estimate histological staining intensity from MRI signals, creating virtual histology maps of mouse brains with enhanced sensitivity and specificity.

bioRxiv · May 1, 2020Bioengineering