Author

J.-Y. Choi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1 Bioengineering· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Organism:fungi (other)· 1

Frequent Co-Authors

C. Ben Mamoun· 2 shared P. Singh· 2 shared X. Che· 2 shared B. Dura· 1 shared C. H. Lee· 1 shared C. Moon· 1 shared C. Park· 1 shared D. Thakral· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersBiochemistry

C. Ben Mamoun

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

DAB-APT: a Fluorescence-Based Assay for Determining Aminopropyl Transferase Activity and Inhibition

P. Singh, J.-Y. Choi, C. Ben Mamoun

The paper develops a fluorescence-based assay, DAB-APT, to measure aminopropyl transferase activity and inhibition, validated with enzymes from S. cerevisiae and P. falciparum.

bioRxiv · Apr 9, 2024Biochemistry

Phospholipase C β4 promotes RANKL-dependent osteoclastogenesis by interacting with MKK3 and p38 MAPK

D.-K. Lee, X. Jin, P.-R. Choi, Y. Cui, X. Che, S. Lee, K. Hur, H.-J. Kim, J.-Y. Choi

This study identifies PLCβ4 as a key regulator of RANKL-induced osteoclastogenesis by interacting with MKK3 and p38 MAPK, showing its potential as a therapeutic target for bone diseases.

bioRxiv · Mar 19, 2024Cell Biology

Vitamin B5 Metabolism is Essential for Vacuolar and Mitochondrial Integrity and Xenobiotic Detoxification in Fungi

J.-Y. Choi, S. Gihaz, M. Munshi, P. Singh, P. Vydyam, P. Hamel, E. M. Adams, K. Fuller, C. Ben Mamoun

This study shows that disrupting the PCA pathway in fungi affects vacuolar integrity, drug detoxification, and susceptibility to antifungal drugs, supporting its potential as a therapeutic target.

bioRxiv · Dec 10, 2023 · PreprintMicrobiology

Peroxiredoxin 5 regulates osteogenic differentiation via interaction with hnRNPK during bone regeneration

E. Cho, X. Che, M. J. Ang, S. Cheon, J. Lee, K. Kim, C. H. Lee, S.-Y. Lee, H.-Y. Yang, C. Moon, C. Park, J.-Y. Choi, T.-H. Lee

This study identifies Prdx5's role in bone regeneration by regulating osteoblast differentiation through interaction with hnRNPK, impacting osteocalcin expression and osteoclast activity.

bioRxiv · Jun 9, 2022Cell Biology

scFTD-seq: freeze-thaw lysis based, portable approach toward high-quality distributed single-cell 3’ mRNA profiling

B. Dura, J.-Y. Choi, K. Zhang, W. Damsky, D. Thakral, M. Bosenberg, J. Craft, R. Fan

scFTD-seq enables high-quality single-cell 3' mRNA profiling using freeze-thaw lysis, offering a portable and flexible workflow for distributed sample processing.

bioRxiv · Oct 19, 2018Bioengineering