Author

C. Henning

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

A. Chakraborty· 1 shared A. Lucko· 1 shared A. S. Lamort· 1 shared C. Ko· 1 shared D. Kati· 1 shared G. Giotopoulou· 1 shared G. Ntaliarda· 1 shared G. T. Stathopoulos· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperMicrobiology

A. Chakraborty

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2 papers

Recent·Most cited

An in vivo inflammatory loop potentiates KRAS blockade

K. A. Arendt, G. Ntaliarda, V. Armenis, D. Kati, C. Henning, G. Giotopoulou, M. A. Pepe, L. V. Klotz, A. S. Lamort, R. A. Hatz, S. Kobold, G. T. Stathopoulos

The paper shows that KRAS-mutant tumors rely on an inflammatory loop involving C-C-motif chemokine ligand 2/interleukin-1β signaling, making them resistant to KRAS inhibitors in vivo but responsive in certain transplant models.

bioRxiv · Apr 19, 2020Cancer Biology

Synchronized infection identifies early rate-limiting steps in the hepatitis B virus life cycle.

A. Chakraborty, C. Ko, C. Henning, A. Lucko, X. Zhuang, J. M. Wettengel, U. Protzer, J. A. McKeating

This study uses synchronized infection to analyze HBV entry and cccDNA formation, finding that most viral particles enter cells but only a small fraction becomes cccDNA, highlighting a rate-limiting step in infection.

bioRxiv · Apr 5, 2020Microbiology