Author

C. Hock

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 2 Assay:proteomics· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:flow cytometry· 1

Frequent Co-Authors

A. Gietl· 2 shared A. Makarov· 2 shared A. Mallone· 2 shared A. Pashkova· 2 shared A. Peterson· 2 shared C. Gericke· 2 shared C. Rickenbach· 2 shared D. Hermanson· 2 shared

Activity by Year

2023-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersImmunology

A. Gietl

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Altered T cell reactivity to β-amyloid-related antigens in early Alzheimer's disease

C. Rickenbach, A. Mallone, L. Haeusle, L. Frei, S. Seiter, C. Sparano, T. Kirabali, K. Blennow, H. Zetterberg, M. T. Ferretti, L. Kulic, C. Hock, R. M. Nitsch, V. Treyer, A. Gietl, C. Gericke

The paper examines immune changes in early Alzheimer's disease stages, finding altered T cell reactivity to β-amyloid-related antigens in preclinical AD and MCI.

bioRxiv · Jun 4, 2024 · PreprintImmunology

Evaluating the performance of the Astral mass analyzer for quantitative proteomics using data independent acquisition

L. R. Heil, N. E. Damoc, T. N. Arrey, A. Pashkova, E. Denisov, J. Petzoldt, A. Peterson, C. Hsu, B. C. Searle, N. Shulman, M. Riffle, B. Connolly, B. X. MacLean, P. M. Remes, M. Senko, , M. J. MacCoss

The paper evaluates the Astral mass analyzer's performance in quantitative proteomics, showing it quantifies 5 times more peptides per unit time than existing Orbitrap mass spectrometers and detects over 5,000 plasma proteins.

bioRxiv · Jun 3, 2023 · PreprintBiochemistry

Parallelized Acquisition of Orbitrap and Astral Analyzers Enables High-Throughput Quantitative Analysis.

H. Stewart, D. Grinfeld, A. Giannakopulos, J. Petzoldt, T. Shanley, M. Garland, E. Denisov, A. Peterson, E. Damoc, M. Zeller, T. Arrey, A. Pashkova, S. Renuse, A. Hakimi, A. Kuehn, , C. Hock

The paper introduces a new hybrid mass spectrometer combining Orbitrap and Astral analyzers to enable faster and more sensitive high-resolution accurate mass MS/MS spectra acquisition for proteomics.

bioRxiv · Jun 2, 2023Cell Biology

Early beta-amyloid accumulation in the brain is associated with peripheral T cell alterations

C. Gericke, T. Kirabali, R. Flury, A. Mallone, C. Rickenbach, L. Kulic, V. Tosevski, C. Hock, R. M. Nitsch, V. Treyer, M. T. Ferretti, A. Gietl

The paper links early brain beta-amyloid accumulation with peripheral T cell changes using mass cytometry and machine learning in AD cohorts.

bioRxiv · Jan 17, 2023Immunology