Author

J. Petzoldt

Thermo Fisher Scientific (Germany)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 4 Systems Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:proteomics· 7 Approach:experimental assay· 6 Research Focus:benchmarking· 4 Organism:human· 4 Organism:yeast· 3 Research Focus:variant calling· 2 Approach:benchmark study· 1 Approach:deep learning· 1

Frequent Co-Authors

Christian Hock· 5 shared Eduard V. Denisov· 5 shared Vlad ZabrouskoviD· 5 shared Alexander MakaroviD· 4 shared Eugen DamociD· 4 shared Tabiwang N. ArreyiD· 4 shared Bernd Hagedorn· 3 shared Hamish I. StewartiD· 3 shared

Activity by Year

2023-2026 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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Curved chords = mutual co-authorship

5 shared papersBiochemistry

Christian Hock

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

High Resolution Multi-Pass Astral Analyzer Quantification Enables Highly Multiplexed 35-Plex Tandem Mass Tag Proteomics

Hamish Stewart, Steven R. Shuken, Christopher Rathje, Julia Kraegenbring, Martin Zeller, Tabiwang N. Arrey, Bernd Hagedorn, Eduard V. Denisov, Robert Ostermann, Dmitry Grinfeld, J. Petzoldt, Daniel Mourad, Philipp Cochems, Florian Bonn, Bernard Delanghe, , Steven P. Gygi

This paper introduces a high-resolution multi-pass Astral analyzer mode for TMT proteomics, enabling 35-plex quantification with improved depth and precision.

bioRxiv · Feb 26, 2026 · PreprintBiochemistry

Higher-Throughput Proteome Profiling Enabled by Parallelized Pre-Accumulation and Optimized Ion Processing in the Orbitrap Astral Zoom Mass Spectrometer

Ulises H. Guzmán, Martin Rykær, Ivo Alexander Hendriks, Hamish I. Stewart, Eduard V. Denisov, Bernd Hagedorn, J. Petzoldt, Arne Kreutzmann, Yannick Mueller, Tabiwang N. Arrey, Immo Colonius, Ole Østergaard, Claire Koenig, Julia Kraegenbring, Kyle L. Fort, , Jesper.V. Olsen

Orbitrap Astral Zoom upgrades enable 270 Hz DIA scanning, identifying 7184 protein groups at 500 samples/day and >12,000 proteins from fractionated HEK293 in 2.7 h.

Molecular & Cellular Proteomics · Jan 10, 2026Peer-reviewedBiochemistry✦ In-depth digest

Evaluation of a prototype Orbitrap Astral Zoom mass spectrometer for quantitative proteomics - Beyond identification lists

Chris Hsu, Nicholas Shulman, Hamish I. Stewart, J. Petzoldt, Anna Pashkova, Deanna L. Plubell, Eduard V. Denisov, Bernd Hagedorn, Nicolaie Eugen Damoc, Brendan MacLean, Philip M. Remes, Jesse D. Canterbury, Alexander Makarov, Christian Hock, Vlad Zabrouskov, , Michael J. MacCoss

This paper evaluates a prototype Orbitrap Astral Zoom mass spectrometer for quantitative proteomics, showing improved performance in ion detection and quantitative precision compared to the standard Orbitrap Astral MS.

Journal of Proteome Research · Oct 22, 2025Peer-reviewedBiochemistry

Evaluating the capabilities of the Astral mass analyzer for single-cell proteomics

Valdemaras Petrosius, Pedro Aragon-Fernandez, Tabiwang N. Arrey, Nil Üresin, Benjamin Furtwängler, Hamish Stewart, Eduard V. Denisov, J. Petzoldt, Amelia C. Peterson, Christian Hock, Eugen Damoc, Alexander Makarov, Vlad Zabrouskov, Bo Torben Porse, Erwin M. Schoof

This study evaluates the Astral mass analyzer's performance in single-cell proteomics using DIA, showing improved proteome depth and quantitative precision for ultra-low input samples.

bioRxiv · Jun 6, 2023 · PreprintSystems Biology

Evaluating the performance of the Astral mass analyzer for quantitative proteomics using data independent acquisition

L. R. Heil, N. E. Damoc, T. N. Arrey, A. Pashkova, E. Denisov, J. Petzoldt, A. Peterson, C. Hsu, B. C. Searle, N. Shulman, M. Riffle, B. Connolly, B. X. MacLean, P. M. Remes, M. Senko, , M. J. MacCoss

The paper evaluates the Astral mass analyzer's performance in quantitative proteomics, showing it quantifies 5 times more peptides per unit time than existing Orbitrap mass spectrometers and detects over 5,000 plasma proteins.

bioRxiv · Jun 3, 2023 · PreprintBiochemistry

Narrow-window DIA: Ultra-fast quantitative analysis of comprehensive proteomes with high sequencing depth

Ulises H. Guzmán, Ana Martínez‐Val, Zilu Ye, Eugen Damoc, Tabiwang N. Arrey, Anna Pashkova, Eduard V. Denisov, J. Petzoldt, Amelia C. Peterson, Florian Harking, Ole Østergaard, Hamish I. Stewart, Yue Xuan, Daniel J. Hermanson, Christian Hock, , Jesper Velgaard Olsen

The paper introduces Narrow-window DIA, a fast proteomics method enabling high-throughput and comprehensive proteome analysis with high precision and accuracy.

bioRxiv · Jun 2, 2023 · PreprintSystems Biology

Parallelized Acquisition of Orbitrap and Astral Analyzers Enables High-Throughput Quantitative Analysis.

H. Stewart, D. Grinfeld, A. Giannakopulos, J. Petzoldt, T. Shanley, M. Garland, E. Denisov, A. Peterson, E. Damoc, M. Zeller, T. Arrey, A. Pashkova, S. Renuse, A. Hakimi, A. Kuehn, , C. Hock

The paper introduces a new hybrid mass spectrometer combining Orbitrap and Astral analyzers to enable faster and more sensitive high-resolution accurate mass MS/MS spectra acquisition for proteomics.

bioRxiv · Jun 2, 2023Cell Biology