C. Illingworth

Epidemiological inference at the threshold of data availability: an influenza A(H1N2)v spillover event in the United Kingdom

The paper estimates the timeline and parameters of an influenza A(H1N2)v spillover event using likelihood-free rejection sampling with limited data.

The airborne transmission of viruses causes tight transmission bottlenecks

The paper shows that airborne viral transmission creates tight bottlenecks due to physical processes, with most infections caused by few viral particles.

Genetic consequences of effective and suboptimal dosing with mutagenic drugs in a hamster model of SARS-CoV-2 infection

This study examines the genetic effects of effective and suboptimal dosing of mutagenic drugs on SARS-CoV-2 in hamsters, finding dose-dependent mutational load and no drug resistance.

A de novo approach to inferring within-host fitness effects during untreated HIV-1 infection

This study uses a novel multi-locus method to infer selection effects on HIV-1 variants in untreated patients, finding a broad distribution of beneficial fitness effects with many variants under weak selection.

Building a mechanistic mathematical model of hepatitis C virus entry

The paper builds a mathematical model of HCV entry, showing sequential receptor interactions and estimating receptor requirements for viral entry.