J. A. Guerra-Assuncao

This study shows that mitochondrial dsRNA from B-ALL cells triggers MSC to become CAFs, linking genetic subtypes to survival outcomes.

This study shows that one-carbon metabolism is essential for Streptococcus pneumoniae virulence, while proline biosynthesis has a strain-dependent role in systemic infection.

This paper shows that disease-attenuated pneumococcal mutants retain epithelial microinvasion but show reduced transmigration and altered inflammatory responses.

This study examines the genetic effects of effective and suboptimal dosing of mutagenic drugs on SARS-CoV-2 in hamsters, finding dose-dependent mutational load and no drug resistance.

This study shows HIV-1 infects resting memory T cells without prior activation, inducing a tissue-resident memory-like phenotype driven by Vpr.