Author

C. J. Hosford

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:E. coli· 2 Research Focus:protein structure prediction· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

J. S. Chappie· 4 shared M. C. Adams· 3 shared C. Court· 2 shared C. J. Schiltz· 2 shared D. L. Court· 2 shared C. J. Schlitz· 1 shared H. J. Macleod· 1 shared H. Pan· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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4 shared papersMicrobiology

J. S. Chappie

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Author profile →

4 papers

Recent·Most cited

The crystal structure of bacteriophage lambda RexA provides novel insights into the DNA binding properties of Rex-like phage exclusion proteins

M. C. Adams, C. J. Schiltz, J. Sun, C. J. Hosford, V. M. Johnson, H. Pan, P. P. Borbat, J. H. Freed, L. C. Thomason, C. Court, D. L. Court, J. S. Chappie

This paper presents the crystal structure of bacteriophage lambda RexA, revealing its DNA binding properties and evolutionary insights into phage exclusion mechanisms.

bioRxiv · Aug 31, 2023Microbiology

Polerovirus N-terminal readthrough domain structures reveal novel molecular strategies for mitigating virus transmission by aphids

C. J. Schiltz, J. R. Wilson, C. J. Hosford, M. C. Adams, S. E. Preising, S. L. DeBlasio, H. J. Macleod, J. Van Eck, M. L. Heck, J. S. Chappie

The paper reports crystal structures of polerovirus NRTDs, showing their dimeric structure and function in inhibiting aphid transmission.

bioRxiv · Apr 10, 2022Plant Biology

Bacteriophage Lambda RexA and RexB Functions Assist the Transition from Lysogeny to Lytic Growth

L. Thomason, D. L. Court, C. J. Schlitz, C. Court, C. J. Hosford, M. C. Adams, J. S. Chappie

The paper shows RexA and RexB proteins assist the transition from lysogenic to lytic growth in bacteriophage lambda by modulating CI and Cro repressors.

bioRxiv · Apr 19, 2021Microbiology

Structural asymmetry governs the assembly and GTPase activity of McrBC restriction complexes

Y. Niu, H. Suzuki, C. J. Hosford, T. Walz, J. S. Chappie

This study reports cryo-EM structures of McrBC complexes from different bacteria, revealing structural asymmetry that governs GTPase activity and nuclease function.

bioRxiv · Jan 30, 2020Biochemistry