Author

C. J. Nicolai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Assay:imaging· 1 Assay:proteomics· 1

Frequent Co-Authors

C. Blaj· 1 shared C. O. Ndubaku· 1 shared D. H. Raulet· 1 shared G. Snyder· 1 shared K. C. Garcia· 1 shared L. Picton· 1 shared L. Zhang· 1 shared M. Danielson· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperImmunology

C. Blaj

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Author profile →

2 papers

Recent·Most cited

Cytosolic bacterial pathogens activate TLR pathways in tumors that synergistically enhance STING agonist cancer therapies

M. Danielson, C. J. Nicolai, T. T. Vo, N. Wolf, T. P. Burke

This study shows that combining STING and TLR agonists enhances anti-tumor effects in mice, with synergistic responses observed when using bacterial pathogens and small molecule TLR agonists.

bioRxiv · Jan 30, 2024Cancer Biology

Powerful synergistic effects of a STING agonist and an IL-2 superkine in cancer immunotherapy against MHC I-deficient and MHC I+ tumors

N. K. Wolf, C. Blaj, L. Picton, G. Snyder, L. Zhang, C. J. Nicolai, C. O. Ndubaku, S. M. McWhirter, K. C. Garcia, D. H. Raulet

The paper combines a STING agonist and an IL-2 superkine to enhance cancer immunotherapy, showing efficacy against both MHC I-deficient and MHC I+ tumors.

bioRxiv · Nov 2, 2021 · PreprintImmunology