Author

C. K. Saha

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

G. C. Atkinson· 3 shared T. Kurata· 3 shared T. Tenson· 3 shared V. Hauryliuk· 3 shared A. Garcia-Pino· 2 shared H. Strahl· 2 shared K. Ernits· 2 shared S. Jimmy· 2 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersMicrobiology

G. C. Atkinson

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3 papers

Recent·Most cited

The structural basis of hyperpromiscuity in a core combinatorial network of Type II toxin-antitoxin and related phage defence systems

K. Ernits, C. K. Saha, T. Brodiazhenko, B. Chouhan, A. Shenoy, J. J. Duque-Pedraza, V. Bojar, J. A. Nakamoto, T. Kurata, A. Egorov, L. Shyrokova, M. J. O. Johansson, T. Mets, A. Rustamova, J. Dzigurski, , G. C. Atkinson

The paper identifies a core combinatorial network of Type II toxin-antitoxin systems, reveals their structural basis for hyperpromiscuity, and validates new TA systems with functional annotations.

bioRxiv · Mar 22, 2023 · PreprintMicrobiology

Panacea: a hyperpromiscuous antitoxin protein domain for the neutralisation of diverse toxin domains

T. Kurata, C. K. Saha, J. A. Buttress, T. Mets, T. Brodiazhenko, K. J. Turnbull, O. F. Awoyomi, S. R. A. Oliveira, S. Jimmy, K. Ernits, M. Delannoy, K. Persson, T. Tenson, H. Strahl, V. Hauryliuk, G. C. Atkinson

The paper identifies and validates a hyperpromiscuous antitoxin domain, Panacea, capable of neutralizing diverse toxin domains across microbial and bacteriophage TA systems.

bioRxiv · May 7, 2021Microbiology

A widespread toxin-antitoxin system exploiting growth control via alarmone signalling

S. Jimmy, C. K. Saha, C. G. Stavropoulos, S. R. A. Oliveira, T. Kurata, A. Koh, A. Cepauskas, H. Takada, T. Tenson, H. Strahl, A. Garcia-Pino, V. Hauryliuk, G. C. Atkinson

The paper identifies toxin-antitoxin systems in bacteria using alarmone signalling, showing how SASs function as toxins and their antitoxins counteract them.

bioRxiv · Sep 4, 2019 · PreprintMicrobiology