Signal-regulated unmasking of the nuclear localization motif in the PAS domain regulates the nuclear translocation of PASK.
M. Xiao, S. Dhungel, R. Azad, D. C. Favaro, R. R. Pushpabai, K. H. Gardner, C. KIKANI
This study identifies a mechanism by which PASK's nuclear translocation is regulated by the interaction between its PAS-A domain and a PIM motif, which is modulated by metabolic signals.
bioRxiv · Sep 6, 2023Biochemistry