Author

C. Kreutz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 5 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 3 Research Focus:protein folding & dynamics· 3 Assay:proteomics· 3 Approach:biophysical modeling· 2 Organism:human· 2 Assay:structural biology· 2 Organism:virus· 2

Frequent Co-Authors

B. Liu· 3 shared C.-C. Chu· 3 shared H. Al-Hashimi· 2 shared H. M. Al-Hashimi· 2 shared H. Shi· 2 shared R. Plangger· 2 shared W. Bildl· 2 shared A. Busse Grawitz· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersBiochemistry

B. Liu

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Author profile →

6 papers

Recent·Most cited

Conformational dynamics and target-dependent myristoyl switch of calcineurin B homologous protein 3

F. Becker, S. Fuchs, L. Refisch, F. Drepper, W. Bildl, U. Schulte, S. Liang, J. I. Heinicke, S. C. Hansen, C. Kreutz, B. Warscheid, B. Fakler, E. V. Mymrikov, C. Hunte

This study investigates the conformational dynamics and target-dependent myristoyl switch of CHP3, revealing that Ca2+ binding and myristoylation independently regulate its function and membrane association.

bioRxiv · Sep 23, 2022Biochemistry

Circulating multimeric immune complexes drive immunopathology in COVID-19

J. Ankerhold, S. Giese, P. Kolb, A. Maul-Pavicic, R. E. Voll, N. Goeppert, K. Ciminski, C. Kreutz, A. Lother, U. Salzer, W. Bildl, T. Welsink, N. Morgenthaler, A. Busse Grawitz, D. Huzly, , V. Falcone

This paper identifies soluble immune complexes as drivers of immunopathology in severe COVID-19 by enhancing FcγRIII activation and forming a vicious cycle of inflammation.

bioRxiv · Jun 25, 2021 · PreprintImmunology

A quantitative model predicts how m6A reshapes the kinetic landscape of nucleic acid hybridization and conformational transitions

B. Liu, H. Shi, A. Rangadurai, F. Nussbaumer, C.-C. Chu, K. A. Erharter, D. A. Case, C. Kreutz, H. M. Al-Hashimi

The paper shows m6A modification slows nucleic acid hybridization by altering conformational dynamics through isomerization pathways.

bioRxiv · Dec 25, 2020Biochemistry

2'-O-methylation alters the RNA secondary structural ensemble

H. Abou Assi, H. Shi, B. Liu, M. C. Clay, K. Erharter, C. Kreutz, C. Holley, H. Al-Hashimi

This study shows that 2'-O-methylation stabilizes alternative RNA secondary structures and increases the lifetime of excited states in the HIV-1 TAR element.

bioRxiv · May 28, 2020 · PreprintBiochemistry

m6A minimally impacts the structure, dynamics, and Rev ARM binding properties of HIV-1 RRE stem IIB

C.-c. Chu, B. Liu, R. Plangger, C. Kreutz, H. Al-Hashimi

This study shows that m6A modification in HIV-1 RRE stem IIB has minimal effects on structure, dynamics, and Rev ARM binding.

bioRxiv · Oct 24, 2019Biochemistry

Dynamic ensemble of HIV-1 RRE stem IIB reveals non-native conformations that disrupt the Rev binding site

C.-C. Chu, R. Plangger, C. Kreutz, H. M. Al-Hashimi

The paper identifies non-native conformations in HIV-1 RRE stem IIB that disrupt Rev binding and are potential targets for anti-HIV therapeutics.

bioRxiv · Dec 18, 2018Biochemistry