Author

S. Giese

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 2 Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Belsom· 1 shared A. Busse Grawitz· 1 shared A. Lother· 1 shared A. Maul-Pavicic· 1 shared B. M. Nijmeijer· 1 shared C. Kreutz· 1 shared C. Speck· 1 shared C. W. Combe· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperBiochemistry

A. Belsom

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Circulating multimeric immune complexes drive immunopathology in COVID-19

J. Ankerhold, S. Giese, P. Kolb, A. Maul-Pavicic, R. E. Voll, N. Goeppert, K. Ciminski, C. Kreutz, A. Lother, U. Salzer, W. Bildl, T. Welsink, N. Morgenthaler, A. Busse Grawitz, D. Huzly, , V. Falcone

This paper identifies soluble immune complexes as drivers of immunopathology in severe COVID-19 by enhancing FcγRIII activation and forming a vicious cycle of inflammation.

bioRxiv · Jun 25, 2021 · PreprintImmunology

The Nef protein of the macrophage tropic HIV-1 strain AD8 counteracts human Bst-2/tetherin

S. Giese, S. P. Lawrence, M. Mazzon, B. M. Nijmeijer, M. Marsh

This study shows that the HIV-1 AD8 strain uses its Nef protein to counteract tetherin restriction in the absence of Vpu, restoring virus release.

bioRxiv · Feb 7, 2020Cell Biology

An integrated workflow for cross-linking/mass spectrometry

M. L. Mendes, L. Fischer, Z. A. Chen, M. Barbon, F. J. O'Reilly, S. Giese, M. Bohlke-Schneider, A. Belsom, T. Dau, C. W. Combe, M. Graham, M. R. Eisele, W. Baumeister, C. Speck, J. Rappsilber

The paper introduces a workflow combining sequential digestion and Xi software to improve cross-linking mass spectrometry detection of protein interactions.

bioRxiv · Mar 6, 2019Biochemistry