A hyper-immunogenic and slow-growing fungal strain induces a murine granulomatous response to cryptococcal infection
C. L. Telzrow, S. Esher Righi, N. Castro-Lopez, A. Campuzano, J. T. Brooks, J. Carney, F. L. Wormley, J. A. Alspaugh
This study identifies a fungal strain with reduced growth and increased immunogenicity that induces granulomas in mice, providing a model for studying cryptococcal latency and reactivation.
bioRxiv · Oct 26, 2021 · PreprintMicrobiology