Author

C. Nichols

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Approach:deep learning· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. F. Lingappa· 1 shared A. Macieik· 1 shared A. Mueller-Schiffmann· 1 shared A. R. Moreira· 1 shared A. Stary-Weinzinger· 1 shared B. Onisko· 1 shared C. L. McCafferty· 1 shared C. L. Telzrow· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

A. F. Lingappa

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Integrative modeling reveals the molecular architecture of the Intraflagellar Transport A (IFT-A) complex

C. L. McCafferty, O. Papoulas, M. A. Jordan, G. Hoogerbrugge, C. Nichols, G. Pigino, D. W. Taylor, J. B. Wallingford, E. M. Marcotte

The paper models the structure of the IFT-A complex using experimental and computational methods, revealing insights into ciliopathy-associated mutations.

bioRxiv · Jul 5, 2022Biochemistry

A Pan-respiratory Antiviral Chemotype Targeting a Host Multiprotein Complex

M. Michon, A. Mueller-Schiffmann, A. F. Lingappa, S. F. Yu, L. Du, F. Deiter, S. Mallesh, J. Crabtree, U. F. Lingappa, A. Macieik, L. Mueller, P. N. Ostermann, M. Andree, O. Adams, H. Schaal, , K

The paper identifies a novel antiviral chemotype effective against multiple respiratory viruses by targeting a host multi-protein complex involved in viral lifecycle and innate immunity.

bioRxiv · Jan 17, 2021Biochemistry

A fungal arrestin protein contributes to cell cycle progression and pathogenesis

C. L. Telzrow, C. Nichols, N. Castro-Lopez, F. L. Wormley, J. A. Alspaugh

This study identifies Ali1, a fungal arrestin protein, as a contributor to cytokinesis and virulence in Cryptococcus neoformans by facilitating lipid synthesis and membrane modification.

mBio · Dec 24, 2019Peer-reviewedMicrobiology

Atomistic basis of opening and conduction in mammalian inward rectifier potassium (Kir2.2) channels

E.-M. Zangerl, S. Lee, G. Maksaev, H. Bernsteiner, F. Ren, P. Yuan, A. Stary-Weinzinger, C. Nichols

The paper investigates the open conformation and K+ ion conduction mechanism in Kir2.2 channels using a forced open mutation and structural analysis.

bioRxiv · May 18, 2019Biophysics