Author

C. Lopez-Iglesias

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:cryo-EM· 1 Organism:human· 1 Organism:mouse· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

A. Gijsbers· 2 shared A. Giladi· 1 shared A. Jaiswal· 1 shared A. Mathew· 1 shared A. Siroy· 1 shared B. Ghesquiere· 1 shared B. S. Dohai· 1 shared B. W. A. M. M. Beulen· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersBiochemistry

A. Gijsbers

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Tuft cells act as regenerative stem cells in the human intestine

L. Huang, J. H. Bernink, A. Giladi, D. Krueger, G. J. F. van Son, M. H. Geurts, G. Busslinger, L. Lin, M. Zandvliet, P. J. Peters, C. Lopez-Iglesias, C. J. Buskens, W. A. Bemelman, H. Begthel, H. Clevers

The paper identifies four human tuft cell states, showing they function as radiation-resistant stem cells capable of regenerating the intestinal epithelium.

bioRxiv · Mar 17, 2024Cell Biology

Priming mycobacterial ESX-secreted protein B to form a channel-like structure

A. Gijsbers, V. Vinciauskaite, A. Siroy, Y. Gao, G. Tria, A. Mathew, N. Sanchez-Puig, C. Lopez-Iglesias, P. P. Peters, R. R. Ravelli

The paper investigates the oligomerization and structural properties of EspB, an ESX-1 substrate, revealing its role in forming a channel-like structure for ESX-1 secretion.

bioRxiv · Jan 2, 2021Biochemistry

Exostosin-1 Glycosyltransferase Regulates Endoplasmic Reticulum Architecture and Dynamics

D. Kerselidou, B. S. Dohai, D. R. Nelson, S. Daakour, N. De Cock, D.-K. Kim, J. Olivet, D. C. El Assal, A. Jaiswal, D. Saha, C. Pain, F. Matthijssens, P. Lemaitre, M. Herfs, J. Chapuis, , J.-C. Twizere

This study shows that Exostosin-1 glycosyltransferase regulates ER morphology and dynamics, affecting cell size and metabolic processes in mammalian cells.

bioRxiv · Sep 2, 2020 · PreprintCell Biology

Automated cryo-EM sample preparation by pin-printing and jet vitrification

R. B. G. Ravelli, F. J. T. Nijpels, R. J. M. Henderikx, G. Weissenberger, S. Thewessem, A. Gijsbers, B. W. A. M. M. Beulen, C. Lopez-Iglesias, P. Peters

This paper introduces a device called VitroJet for automated cryo-EM sample preparation, which reduces waste and improves reproducibility by using pin-printing and jet vitrification.

bioRxiv · May 28, 2019 · PreprintBiophysics