Author

M. H. Geurts

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

H. Clevers· 2 shared A. C. Rios· 1 shared A. Cleven· 1 shared A. D. Meringa· 1 shared A. Giladi· 1 shared A. K. L. Wezenaar· 1 shared A. M. M. Eggermont· 1 shared C. J. Buskens· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

H. Clevers

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Author profile →

2 papers

Recent·Most cited

Tuft cells act as regenerative stem cells in the human intestine

L. Huang, J. H. Bernink, A. Giladi, D. Krueger, G. J. F. van Son, M. H. Geurts, G. Busslinger, L. Lin, M. Zandvliet, P. J. Peters, C. Lopez-Iglesias, C. J. Buskens, W. A. Bemelman, H. Begthel, H. Clevers

The paper identifies four human tuft cell states, showing they function as radiation-resistant stem cells capable of regenerating the intestinal epithelium.

bioRxiv · Mar 17, 2024Cell Biology

Behavioral-transcriptomic landscape of engineered T cells targeting human cancer organoids

J. F. Dekkers, M. Alieva, A. Cleven, F. Keramati, P. Brazda, H. G. Rebel, A. K. L. Wezenaar, J. Puschhof, M.-B. Buchholz, M. Barrera Roman, I. Johanna, A. D. Meringa, D. Fasci, M. H. Geurts, H. C. R. Ariese, , A. C. Rios

The paper develops BEHAV3D, a 3D imaging-transcriptomics platform to study T cell behavior and molecular mechanisms in cancer organoids, identifying a super engager cluster with unique gene signatures and IFN-I priming capabilities.

bioRxiv · May 5, 2021Cancer Biology