Cooperative phagocytosis underlies macrophage immunotherapy of solid tumours and initiates a broad anti-tumour IgG response
J. C. Andrechak, L. J. Dooling, B. H. Hayes, S. Kadu, W. Zhang, R. Pan, M. Vashisth, J. Irianto, C. M. Alvey, D. E. Discher
This study shows engineered macrophages using cooperative phagocytosis eliminate solid tumours and induce anti-tumour IgG, improving immunotherapy outcomes.
bioRxiv · Jan 1, 2022Bioengineering