Author

J. M. Schenkel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:scRNA-seq· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Bhutkar· 2 shared T. Jacks· 2 shared A. Ghosh· 1 shared A. H. Sharpe· 1 shared A. I. Daud· 1 shared A. Li· 1 shared A. Regev· 1 shared C. Delaney· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersCancer Biology

A. Bhutkar

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Author profile →

3 papers

Recent·Most cited

Modeling diverse genetic subtypes of lung adenocarcinoma with a next-generation alveolar type 2 organoid platform

S. Naranjo, C. M. Cabana, L. M. LaFave, P. M. Westcott, R. Romero, A. Ghosh, L. Z. Liao, J. M. Schenkel, I. Del Priore, A. Bhutkar, D. Yang, T. Jacks

This study develops a reliable alveolar type 2 organoid platform to model diverse genetic subtypes of lung adenocarcinoma in vitro and in vivo.

bioRxiv · Dec 7, 2021 · PreprintCancer Biology

Single-cell analyses identify circulating anti-tumor CD8 T cells and markers for their enrichment

K. E. Pauken, O. Shahid, K. A. Lagattuta, K. M. Mahuron, J. M. Luber, M. M. Lowe, L. Huang, C. Delaney, J. M. Long, M. E. Fung, K. Newcomer, K. K. Tsai, M. Chow, S. Guinn, J. R. Kuchroo, , M. Singer

The paper identifies circulating anti-tumor CD8 T cells using single-cell RNA sequencing and TCR sequencing, and develops marker panels for their detection in mice and melanoma patients.

bioRxiv · Sep 30, 2020Immunology

Longitudinal single cell profiling of regulatory T cells identifies IL-33 as a driver of tumor immunosuppression

A. Li, R. H. Herbst, D. Canner, J. M. Schenkel, O. C. Smith, J. Y. Kim, M. Hillman, A. Bhutkar, M. S. Cuoco, C. G. Rappazzo, P. Rogers, C. Q. Dang, O. Rozenblatt-Rosen, L. Cong, M. Birnbaum, , T. Jacks

The paper identifies IL-33 as a driver of tumor immunosuppression by analyzing longitudinal single-cell RNA-Seq data of regulatory T cells in a mouse model of lung adenocarcinoma.

bioRxiv · Jan 6, 2019 · PreprintCancer Biology