R. Romero

The neuroendocrine transition in prostate cancer is dynamic and dependent on ASCL1

This study identifies ASCL1 as a critical driver of neuroendocrine lineage transition in prostate cancer using an in vivo model and spatial transcriptomics.

The vaginal microbiota of pregnant women varies with gestational age, maternal age, and parity

This study characterizes the vaginal microbiota in pregnant African-American women across gestation, identifying key factors like gestational age and parity that influence its composition.

Homeostatic macrophages prevent preterm birth and improve neonatal outcomes by mitigating in utero sterile inflammation

The paper shows that M2 macrophages prevent preterm birth and improve neonatal outcomes by reducing in utero sterile inflammation in mice.

MNRR1 activation by nitazoxanide abrogates lipopolysaccharide- induced preterm birth in mice

The paper shows that nitazoxanide prevents preterm birth in mice by activating MNRR1, which counteracts inflammation caused by intra-amniotic LPS.

Is there a placental microbiota? A critical review and re-analysis of published placental microbiota datasets

This paper re-analyzes 15 placental microbiota datasets to determine if a placental microbiota exists, finding that bacterial signals likely arise from contamination rather than a true microbiota.

Bacterial profiles of the human placenta from term and preterm deliveries

This study investigates bacterial profiles in term and preterm placentas, finding no placental microbiota in term pregnancies but variable bacterial presence in preterm cases, influenced by delivery mode.

The single-cell atlas of the murine reproductive tissues during preterm labor

This study uses scRNA-seq to create a single-cell atlas of murine reproductive tissues during infection-induced preterm labor, identifying gene expression signatures and intercellular communication changes.

Microbiota of the pregnant mouse: characterization of the bacterial communities in the oral cavity, lung, intestine, and vagina through culture and DNA sequencing

This study characterizes the microbiota of pregnant mice at four body sites using culture and DNA sequencing, finding that vaginal microbiota can be cultured and show similarities to human vaginal microbiota.

Modeling diverse genetic subtypes of lung adenocarcinoma with a next-generation alveolar type 2 organoid platform

This study develops a reliable alveolar type 2 organoid platform to model diverse genetic subtypes of lung adenocarcinoma in vitro and in vivo.

LACK OF EVIDENCE FOR A VIABLE MICROBIOTA IN MURINE AMNIOTIC FLUID

This study investigates whether murine amniotic fluid contains a viable microbiota, finding no evidence of a viable microbial community despite detecting bacterial DNA.

Lack of evidence for microbiota in the placental and fetal tissues of rhesus macaques

This study investigates the presence of viable bacterial communities in fetal and placental tissues of rhesus macaques using culture, qPCR, and DNA sequencing, finding no consistent evidence of microbial colonization.

PARTITIONING AMONG NICHE AND NEUTRAL EXPLANATIONS FOR METACOMMUNITY PATTERNS IN CERRADO STREAM FISH COMMUNITIES

The paper partitions metacommunity patterns in Cerrado stream fish communities between niche and neutral explanations, finding species sorting mechanisms are more important than neutral processes.

No consistent evidence for microbiota in murine placental and fetal tissues

This study investigates the presence of bacterial communities in placental and fetal tissues of mice using culture, qPCR, and 16S rRNA sequencing, finding no consistent evidence of microbiota.

Evolution of embryo implantation was enabled by the origin of decidual cells in eutherian mammals

This study identifies the evolutionary mechanism by which decidual cells in eutherian mammals suppressed IL17A signaling to enable embryo implantation.