Author

C. M. Lutz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Animal Behavior & Cognition· 2 Bioengineering· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 5 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Research Focus:clustering· 2 Approach:deep learning· 2 Research Focus:gene regulatory network inference· 2 Research Focus:host-pathogen & immune response· 2

Frequent Co-Authors

S. A. Murray· 2 shared V. Kumar· 2 shared A. Chavez· 1 shared A. Peer· 1 shared A. R. Agra de Almeida Quadros· 1 shared A. Zuberi· 1 shared B. Geuther· 1 shared B. Q. Geuther· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersBioengineering

S. A. Murray

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Author profile →

5 papers

Recent·Most cited

Characterization of Collaborative Cross mouse founder strain CAST/EiJ as a novel model for lethal COVID-19

C. Baker, D. Duso, N. Kothapalli, T. Hart, S. Casey, L. Kummer, T. Cookenham, J. Hvizdos, K. Lanzer, P. Vats, P. Shanbhag, I. Bell, M. Tighe, K. Travis, F. Szaba, , N. Rosenthal

The paper characterizes the CAST/EiJ mouse strain as a model for severe COVID-19 by showing it develops high viral burdens, severe lung pathology, and cytokine dysregulation leading to mortality.

bioRxiv · Apr 26, 2024Immunology

Stathmin-2 loss leads to neurofilament-dependent axonal collapse driving motor and sensory denervation

J. Lopez-Erauskin, M. Bravo-Hernandez, M. Presa, M. W. Baughn, Z. Melamed, M. S. Beccari, A. R. Agra de Almeida Quadros, A. Zuberi, K. Ling, O. Platoshyn, E. Nino-Jara, I. S. Ndayambaje, O. Arnold-Garcia, M. McAlonis-Downes, L. Cabrera, , C. Lagier-Tourenne

This study shows that loss of stathmin-2 causes neurofilament-dependent axonal collapse, leading to motor and sensory deficits and denervation in mice.

bioRxiv · Dec 11, 2022Cell Biology

Focused ultrasound-mediated brain genome editing

Y.-H. Lao, R. Ji, J. K. Zhou, K. J. Snow, N. Kwon, E. Saville, S. He, S. Chauhan, C.-W. Chi, M. S. Datta, H. Zhang, C. H. Quek, S. Cai, M. Li, Y. Gaitan, , K. W. Leong

This paper demonstrates a method to edit the brain genome in mammals using focused ultrasound to temporarily open the blood-brain barrier for CRISPR/Cas9 delivery via intravenous injection.

bioRxiv · Dec 10, 2022Bioengineering

Gait-level analysis of mouse open field behavior using deep learning-based pose estimation

K. Sheppard, J. Gardin, G. Sabnis, A. Peer, M. Darrell, S. Deats, B. Geuther, C. M. Lutz, V. Kumar

This paper develops a deep learning-based method to analyze mouse gait and posture in open field behavior, showing high heritability and identifying ASD-related gait deficits.

bioRxiv · Dec 29, 2020 · PreprintAnimal Behavior & Cognition

Robust Mouse Tracking in Complex Environments using Neural Networks

B. Q. Geuther, S. P. Deats, K. J. Fox, S. A. Murray, R. E. Braun, J. K. White, E. J. Chesler, C. M. Lutz, V. Kumar

This paper develops a neural network-based mouse tracker for complex environments, finding that an encoder-decoder segmentation model achieves high accuracy with minimal training data.

bioRxiv · Jul 21, 2018Animal Behavior & Cognition