Author

C. McCaughey

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:bacteria (other)· 1 Assay:metabolomics· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

A. Ali· 2 shared C. G. G. Bamford· 2 shared D. Courtney· 2 shared G. Lopez Campos· 2 shared K. Mills· 2 shared L. Broadbent· 2 shared O. Touzelet· 2 shared A. McAtamney· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersImmunology

A. Ali

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A label-free approach for relative spatial quantitation of c-di-GMP in microbial biofilms

C. McCaughey, M. Trebino, A. McAtamney, R. Isenberg, M. J. Mandel, F. Yildiz, L. Sanchez

This study develops a label-free method to detect spatial changes in c-di-GMP levels in microbial biofilms using MALDI-MSI and applies it to three bacterial species.

bioRxiv · Oct 10, 2023Microbiology

An Endogenously activated antiviral state restricts SARS-CoV-2 infection in differentiated primary airway epithelial cells

L. Broadbent, C. G. G. Bamford, G. Lopez Campos, S. Manzoor, D. Courtney, A. Ali, O. Touzelet, C. McCaughey, K. Mills, U. Power

The paper shows that an endogenous IFNλ pathway provides resistance to SARS-CoV-2 in airway epithelial cells, with high baseline IFNλ correlating with resistance.

bioRxiv · Aug 17, 2021Immunology

Collaboration Between Host and Viral Factors Shape SARS-CoV-2 Evolution

C. G. G. Bamford, L. Broadbent, E. Aranday Cortes, M. McCabe, J. McKenna, D. Courtney, O. Touzelet, A. Ali, G. Roberts, G. Lopez Campos, D. Simpson, C. McCaughey, D. Fairley, K. Mills, U. F. Power, The Breathing Together Consortium

This study investigates how viral and host factors influence SARS-CoV-2 evolution in vitro, identifying genetic changes and their impact on viral fitness in different cell types.

bioRxiv · Jul 16, 2021 · PreprintMicrobiology