MicrobiologybioRxivPreprint
Legionella pneumophila inhibits type I interferon signaling to avoid cell-intrinsic host cell defense.
C. N. S. Allen, D. A. Banks, M. Shuster…·V. Briken
This study shows Legionella pneumophila inhibits the IFN-β signaling pathway but not IFN-ψ, using its type IV secretion system, and this inhibition occurs downstream of STAT1 and STAT2 phosphorylation.
DOI 10.1101/2022.12.21.521455