Myc controls IL-15-driven expansion and translational machinery of NK cells
H. J. Khameneh, N. Fonta, A. Zenobi, C. Niogret, P. Ventura, C. Guerra, I. Kwee, A. Rinaldi, M. Pecoraro, R. Geiger, A. Cavalli, F. Bertoni, E. E. Vivier, A. Trumpp, G. Guarda
This study shows that Myc is essential for NK cell development, expansion, and anticancer immunity by regulating translational machinery and IL-15 responses.
bioRxiv · Dec 20, 2022 · PreprintImmunology