Detection of the HIV-1 accessory proteins Nef and Vpu by flow cytometry represents a new tool to study their functional interplay within a single infected CD4+ T cell
J. Prevost, J. Richard, R. Gasser, H. Medjahed, F. Kirchhoff, B. H. Hahn, J. C. Kappes, C. Ochsenbauer, R. Duerr, A. Finzi
The paper develops a flow cytometry method to detect HIV-1 Nef and Vpu in CD4+ T cells, showing Vpu cannot compensate for Nef absence in ADCC susceptibility.
bioRxiv · Nov 3, 2021Microbiology