Author

E. J. Allen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 2 Cancer Biology· 1 Microbiology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Assay:imaging· 3 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Organism:non-human primate· 1

Frequent Co-Authors

T. J. Hope· 4 shared A. M. Carias· 2 shared E. Matias· 2 shared F. J. Villinger· 2 shared K. A. Rogers· 2 shared M. Arainga· 2 shared M. D. McRaven· 2 shared M. R. Anderson· 2 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersCell Biology

T. J. Hope

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Nonlinear progression during the occult transition establishes cancer lethality

J. D. Ginzel, H. Chapman, J. E. Sills, E. J. Allen, L. S. Barak, R. D. Cardiff, A. D. Borowsky, H. K. Lyerly, B. W. Rogers, J. C. Snyder

This study shows that cancer progression is nonlinear, with a critical occult transition leading to lethal tumors before detection, challenging the linear model of cancer growth.

bioRxiv · Apr 23, 2024Cancer Biology

Localization of infection in neonatal rhesus macaques after oral viral challenge

T. J. Hope, R. A. Taylor, M. D. McRaven, A. M. Carias, M. R. Anderson, E. Matias, M. Arainga, E. J. Allen, K. A. Rogers, S. Gupta, V. Kulkarni, S. Lakhashe, R. Lorenzo-Redondo, Y. Thomas, A. Strickland, , R. M. Ruprecht

This study uses PET and fluorescent microscopy to track HIV distribution in neonatal rhesus macaques after oral challenge, showing virions localize to the rectal mucosa by four hours and the intestine contains the most infected cells at 96 hours.

PLOS Pathogens · Nov 18, 2021Peer-reviewedCell Biology

Simultaneous in vivo Pharmacokinetics and Pharmacodynamics of TDF Intravaginal Ring during High-dose Vaginal SHIV Challenge in Pigtail Macaques

K. Klotnik Halavaty, A. Ott, D. Maric, J. Su, E. Matias, E. J. Allen, A. Martin, L. E. Pereira, F. Deyounks, J. Smith, P. F. Kiser, T. J. Hope

This study examines TFV distribution and protection efficacy of a TDF IVR in macaques during high-dose SIV challenge, finding uneven TFV distribution and incomplete protection.

bioRxiv · Jun 29, 2021 · PreprintPharmacology & Toxicology

PET/CT targeted tissue sampling reveals virus specific dIgA can alter the distribution and localization of HIV after rectal exposure

R. A. Taylor, S. Xiao, A. M. Carias, M. D. McRaven, D. N. Thakkar, M. Arainga, E. J. Allen, K. A. Rogers, S. C. Kumarapperuma, S. Gong, A. J. Fought, M. R. Anderson, Y. Thomas, J. R. Schneider, B. Goins, , T. J. Hope

The paper uses PET/CT and fluorescent microscopy to show dIgA increases HIV virion distribution and penetration in colorectal tissue and lymph nodes after exposure.

bioRxiv · Dec 23, 2020Cell Biology

Longitudinal bioluminescent imaging of HIV-1 infection during antiretroviral therapy and treatment interruption in humanized mice

J. D. Ventura, J. Beloor, E. J. Allen, T. Zhang, K. Haugh, P. Uchil, C. Ochsenbauer, C. Kieffer, P. Kumar, T. J. Hope, W. Mothes

This study uses bioluminescent imaging to monitor HIV-1 infection dynamics in humanized mice during and after antiretroviral therapy, showing rebound in previously infected lymphoid tissues.

bioRxiv · Aug 24, 2019Microbiology