Author

C. P. Roca

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Assay:flow cytometry· 1

Frequent Co-Authors

A. Liston· 2 shared J. Dooley· 2 shared A. Brajic· 1 shared A. Moudra· 1 shared B. Brown· 1 shared C. E. Whyte· 1 shared C. Whyte· 1 shared E. Pasciuto· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersImmunology

A. Liston

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2 papers

Recent·Most cited

The tissue-resident regulatory T cell pool is shaped by transient multi-tissue migration and a conserved residency program

O. Burton, O. Bricard, S. Tareen, V. Gergelits, S. Andrews, C. P. Roca, C. Whyte, S. Junius, A. Brajic, E. Pasciuto, M. Ali, P. Lemaitre, S. M. Schlenner, H. Ishigame, B. Brown, , A. Liston

The paper analyzes tissue-resident regulatory T cells (Tregs) in non-lymphoid organs, showing they share phenotypes, transient residency, and TCR sequences, with tissue-agnostic re-entry capabilities.

bioRxiv · Aug 14, 2023Immunology

Context-dependent effects of IL-2 rewire immunity into distinct cellular circuits

C. E. Whyte, K. Singh, O. T. Burton, M. Aloulou, A. Moudra, C. P. Roca, F. J. Naranjo, F. Lombard-Vadnais, L. Kouser, T. Hochepied, T. Y. F. Halim, S. Schlenner, S. Lesage, J. Dooley, A. Liston

This study identifies context-dependent effects of IL-2 on immune circuits by rewiring its production sources in mice, revealing distinct cellular responses and potential adverse effects.

bioRxiv · Dec 18, 2020Immunology