Author

O. T. Burton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

A. Liston· 2 shared A. J. Spencer· 1 shared A. Moudra· 1 shared A. Silva-Cayetano· 1 shared C. Conceicao· 1 shared C. E. Whyte· 1 shared C. Noble· 1 shared C. P. Roca· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersImmunology

A. Liston

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2 papers

Recent·Most cited

Context-dependent effects of IL-2 rewire immunity into distinct cellular circuits

C. E. Whyte, K. Singh, O. T. Burton, M. Aloulou, A. Moudra, C. P. Roca, F. J. Naranjo, F. Lombard-Vadnais, L. Kouser, T. Hochepied, T. Y. F. Halim, S. Schlenner, S. Lesage, J. Dooley, A. Liston

This study identifies context-dependent effects of IL-2 on immune circuits by rewiring its production sources in mice, revealing distinct cellular responses and potential adverse effects.

bioRxiv · Dec 18, 2020Immunology

A booster dose enhances immunogenicity of the COVID-19 vaccine candidate ChAdOx1 nCoV-19 in aged mice

A. Silva-Cayetano, W. S. Foster, S. Innocentin, S. Belij-Rammerstorfer, A. J. Spencer, O. T. Burton, S. Fra-Bido, J. L. Lee, N. Thakur, C. Conceicao, D. Wright, J. Barrett, N. Evans-Bailey, C. Noble, D. Bailey, , M. A. Linterman

This study shows that a booster dose of the ChAdOx1 nCoV-19 vaccine increases immune response in aged mice compared to a single dose.

bioRxiv · Oct 27, 2020Immunology