Author

A. Moudra

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell type annotation· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:host-pathogen & immune response· 2 Assay:CITE-seq· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

A. Drobek· 2 shared A. Liston· 2 shared D. Cizkova· 2 shared J. Dooley· 2 shared J. Kreisinger· 2 shared K. Singh· 2 shared L. Schmiedova· 2 shared M. Pribikova· 2 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

A. Drobek

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Author profile →

4 papers

Recent·Most cited

Investigating the effects of radiation, T cell depletion, and bone marrow transplantation on murine gut microbiota

J. Kreisinger, J. Dooley, K. Singh, D. Cizkova, L. Schmiedova, B. Bendova, A. Liston, A. Moudra

This study examines how radiation, T cell depletion, and bone marrow transplantation affect the gut microbiota in mice, revealing region-specific changes and the impact of T cells on microbial composition.

bioRxiv · Jul 10, 2023Immunology

Context-dependent effects of IL-2 rewire immunity into distinct cellular circuits

C. E. Whyte, K. Singh, O. T. Burton, M. Aloulou, A. Moudra, C. P. Roca, F. J. Naranjo, F. Lombard-Vadnais, L. Kouser, T. Hochepied, T. Y. F. Halim, S. Schlenner, S. Lesage, J. Dooley, A. Liston

This study identifies context-dependent effects of IL-2 on immune circuits by rewiring its production sources in mice, revealing distinct cellular responses and potential adverse effects.

bioRxiv · Dec 18, 2020Immunology

Phenotypic and clonal stability of antigen-inexperienced memory-like T cells across the genetic background, hygienic status, and aging

A. Moudra, V. Niederlova, J. Novotny, L. Schmiedova, J. Kubovciak, T. Matejkova, A. Drobek, M. Pribikova, R. Stopkova, D. Cizkova, A. Neuwirth, J. Michalik, K. Krizova, T. Hudcovic, M. Kolar, , O. Stepanek

This study characterizes antigen-inexperienced memory-like T cells across genetic backgrounds, hygienic conditions, and aging, showing their clonal stability and distinct subsets defined by CD122 expression.

bioRxiv · Sep 1, 2020Immunology

Strong homeostatic TCR signals induce formation of self-tolerant virtual memory CD8 T cells

A. Drobek, A. Moudra, D. Mueller, M. Huranova, V. Horkova, M. Pribikova, R. Ivanek, S. Oberle, D. Zehn, K. D. McCoy, P. Draber, O. Stepanek

The paper shows that virtual memory CD8 T cells arise from strongly self-reactive T cells and are regulated by CD8-Lck stoichiometry, but do not exhibit increased autoimmune potential.

bioRxiv · Oct 13, 2017Immunology