Author

C. Pukhrambam

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Assay:ATAC-seq· 1 Organism:E. coli· 1 Assay:structural biology· 1

Frequent Co-Authors

B. E. Nickels· 2 shared J. T. Winkelman· 2 shared R. H. Ebright· 2 shared A. Tareen· 1 shared D. M. Taylor· 1 shared H. Vu· 1 shared I. O. Vvedenskaya· 1 shared J. B. Kinney· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersBiochemistry

B. E. Nickels

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2 papers

Recent·Most cited

Structural and mechanistic basis of σ-dependent transcriptional pausing

C. Pukhrambam, V. Molodtsov, M. Kooshkbaghi, A. Tareen, H. Vu, K. S. Skalenko, M. Su, Y. Zhou, J. T. Winkelman, J. B. Kinney, R. H. Ebright, B. E. Nickels

This paper identifies the structural basis of σ-dependent transcriptional pausing by showing that it involves backtracked or scrunched states of RNA polymerase, depending on the presence of GreB.

bioRxiv · Jan 24, 2022Biochemistry

XACT-seq comprehensively defines the promoter-position and promoter-sequence determinants for initial-transcription pausing

J. T. Winkelman, C. Pukhrambam, I. O. Vvedenskaya, Y. Zhang, D. M. Taylor, P. Shah, R. H. Ebright, B. E. Nickels

XACT-seq identifies promoter-position and sequence determinants for initial-transcription pausing in Escherichia coli by measuring RNAP-active-center position relative to DNA with single-nucleotide resolution.

bioRxiv · Dec 21, 2019Biochemistry