Author

K. S. Skalenko

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:chromatin & epigenetic regulation· 2 Organism:E. coli· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Assay:metabolomics· 1

Frequent Co-Authors

B. E. Nickels· 2 shared J. B. Kinney· 2 shared J. T. Winkelman· 2 shared P. Shah· 2 shared R. H. Ebright· 2 shared A. Cope· 1 shared A. Tareen· 1 shared C. Pukhrambam· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBiochemistry

B. E. Nickels

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3 papers

Recent·Most cited

Linking genotypic and phenotypic changes in the E. coli Long-Term Evolution Experimentusing metabolomics

J. S. Favate, K. S. Skalenko, E. Chiles, X. Su, S. S. Yadavalli, P. Shah

The paper links mutations to metabolic changes and fitness in E. coli from the LTEE using metabolomics and integrates this with mutation and expression data.

bioRxiv · Feb 15, 2023 · PreprintEvolutionary Biology

Structural and mechanistic basis of σ-dependent transcriptional pausing

C. Pukhrambam, V. Molodtsov, M. Kooshkbaghi, A. Tareen, H. Vu, K. S. Skalenko, M. Su, Y. Zhou, J. T. Winkelman, J. B. Kinney, R. H. Ebright, B. E. Nickels

This paper identifies the structural basis of σ-dependent transcriptional pausing by showing that it involves backtracked or scrunched states of RNA polymerase, depending on the presence of GreB.

bioRxiv · Jan 24, 2022Biochemistry

Promoter-sequence determinants and structural basis of primer-dependent transcription initiation in Escherichia coli

K. S. Skalenko, L. Li, Y. Zhang, I. O. Vvedenskaya, J. T. Winkelman, A. Cope, D. M. Taylor, P. Shah, R. H. Ebright, J. B. Kinney, Y. Zhang, B. E. Nickels

The paper identifies promoter sequence determinants and structural basis of primer-dependent transcription initiation in E. coli using MASTER and biochemical studies.

bioRxiv · Apr 6, 2021Biochemistry