Pharmacology & ToxicologyNeuropharmacologyPeer-reviewed
Antidepressant-like effect of losartan involves TRKB transactivation from angiotensin receptor type 2 (AGTR2) and recruitment of FYN
C. R. Alves Faria Diniz, P. Casarotto, S. M. Fred…·S. R. L. Joca
This study shows losartan has antidepressant-like effects via AGTR2-mediated TRKB transactivation and FYN recruitment in brain regions.
DOI 10.1016/j.neuropharm.2018.03.011